Cayman Chemical's Caspase-8 Monoclonal Antibody (Clone 90A992) is a Mouse monoclonal antibody. This antibody has been shown to work in applications such as: Flow Cytometry, Immunohistochemistry, Immunohistochemistry - fixed, and Western Blot.
Description
Antigen: human caspase-8 amino acids PVETDSEEQP
• Host: mouse, clone 90A992
• Isotype: IgG1
• Cross Reactivity: (+) human, chimpanzee, and Rhesus monkey caspase-8
• Application(s): FC, IHC (paraffin-embedded tissue), and WB
• Caspase-8 forms a direct link between the activation of CD95 and the caspase pathway. Overexpression of caspase-8 induces apoptosis, which can be blocked by inhibitors specific for the ICE family